When the player meets her she is in a feud with Bertram Tung, a Nosferatu elder, that the player must persuade her to call off. She is a Malkavian with pretensions to be a Ventrue (visible in her affected distaste of the Nosferatu). Jeanette makes a point of flirting with everyone including the player, while Therese works hard to attain power and the favour of the Camarilla. At the Asylum, Jeanette handles PR while Therese takes care of the business end. She resents her sister Jeanette for her flamboyance and promiscuity (despite being a vampire and technically undead).

Therese is the owner of the Asylum nightclub and the self-proclaimed Baroness of Santa Monica.